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基于DNA鏈置換的三級聯(lián)組合分子邏輯電路設計

孫軍偉 李智 王延峰

孫軍偉, 李智, 王延峰. 基于DNA鏈置換的三級聯(lián)組合分子邏輯電路設計[J]. 電子與信息學報, 2020, 42(6): 1401-1409. doi: 10.11999/JEIT190847
引用本文: 孫軍偉, 李智, 王延峰. 基于DNA鏈置換的三級聯(lián)組合分子邏輯電路設計[J]. 電子與信息學報, 2020, 42(6): 1401-1409. doi: 10.11999/JEIT190847
Junwei SUN, Zhi LI, Yanfeng WANG. Design of Three-cascade Combinatorial Molecular Logic Circuit Based on DNA Strand Displacement[J]. Journal of Electronics & Information Technology, 2020, 42(6): 1401-1409. doi: 10.11999/JEIT190847
Citation: Junwei SUN, Zhi LI, Yanfeng WANG. Design of Three-cascade Combinatorial Molecular Logic Circuit Based on DNA Strand Displacement[J]. Journal of Electronics & Information Technology, 2020, 42(6): 1401-1409. doi: 10.11999/JEIT190847

基于DNA鏈置換的三級聯(lián)組合分子邏輯電路設計

doi: 10.11999/JEIT190847 cstr: 32379.14.JEIT190847
基金項目: 國家重點研發(fā)項目(2017YFE0103900),國家自然科學基金 (U1804262, 61603348, 61632002),中原千人計劃(204200510003),食管癌防治國家重點實驗室開放基金(K2020-0010, K2020-0011)
詳細信息
    作者簡介:

    孫軍偉:男,1984年生,副教授,研究方向為生物信息處理與控制

    李智:男,1994年生,碩士生,研究方向為DNA計算,DNA鏈置換

    王延峰:男,1973年生,教授,研究方向為生物信息處理與控制

    通訊作者:

    王延峰 yanfengwang@yeah.net

  • 中圖分類號: TP301

Design of Three-cascade Combinatorial Molecular Logic Circuit Based on DNA Strand Displacement

Funds: The National Key R and D Program of China for International S and T Cooperation Projects (2017YFE0103900), The National Natural Science Foundation of China (U1804262, 61603348, 61632002), The Zhongyuan Thousand Talents Program (204200510003), The Open Fund of State Key Laboratory of Esophageal Cancer Prevention and Treatment (K2020-0010, K2020-0011)
  • 摘要: DNA計算研究內容繁多復雜,DNA復雜邏輯電路的搭建屬于DNA計算的一個重要研究分支,其中邏輯門的構建屬于DNA復雜邏輯電路搭建的基礎研究,設計出更為簡單的邏輯門可以為研究者搭建復雜電路提供參考,節(jié)省基礎研究的寶貴時間。針對上述問題,該文利用使能控制端思想,采用DNA鏈置換技術,設計了與或、與非或非和異或同或3種DNA組合邏輯門。結果顯示,設計的3種組合邏輯門可實現(xiàn)6種邏輯運算功能,并利用所構建的組合邏輯門成功構造了多級聯(lián)組合分子邏輯電路,為DNA計算提供了更多的解決方案,促進了DNA計算機的發(fā)展。
  • 圖  1  與或組合邏輯門

    圖  2  與或組合邏輯門仿真圖

    圖  3  與非或非組合邏輯門

    圖  4  與非或非組合邏輯門仿真圖

    圖  5  異或同或組合邏輯門

    圖  6  異或同或組合邏輯門仿真圖

    圖  7  4輸入3級聯(lián)組合邏輯電路

    圖  8  四輸入三級聯(lián)組合邏輯電路

    表  1  4輸入3級聯(lián)組合邏輯電路真值表

    序號C1/C2C3/C4C5/C6Y序號C1/C2C3/C4C5/C6Y
    1ON/OFFON/OFFON/OFF(ABC)'⊕D6OFF/ONOFF/ONON/OFF((A+B)+C)'⊕D
    2ON/OFFON/OFFOFF/ON(ABC)'⊙D7OFF/ONON/OFFOFF/ON((A+B)C)'⊙D
    3ON/OFFOFF/ONON/OFF((AB)+C)'⊕D8OFF/ONON/OFFON/OFF((A+B)C)'⊕D
    4ON/OFFOFF/ONOFF/ON((AB)+C)'⊙D9OFF/OFFOFF/OFFOFF/OFFOFF
    5OFF/ONOFF/ONOFF/ON((A+B)+C)'⊙D10ON/ONON/ONON/ONON
    下載: 導出CSV
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  • 加載中
圖(8) / 表(1)
計量
  • 文章訪問數(shù):  2523
  • HTML全文瀏覽量:  834
  • PDF下載量:  115
  • 被引次數(shù): 0
出版歷程
  • 收稿日期:  2019-11-01
  • 修回日期:  2020-04-18
  • 網(wǎng)絡出版日期:  2020-05-13
  • 刊出日期:  2020-06-22

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